The Oklahoma Shared Clinical and Translational Resources

The OSCTR is funded by the National Institutes of Health as part of its IDeA-CTR program. We have the mission to serve as a catalyst for clinical and translational research that improves health and healthcare for Oklahomans, to provide training and infrastructure to help junior investigators to launch independent research careers, and to expand the opportunities of IDeA states and Oklahoma communities to participate in research that improves the health of our residents. 

Oklahoma Clinical and Translational Science Institute

 

OCTSI is the home of the OSCTR, as well as clinical research services and dissemination and implementation resources to help improve the delivery of healthcare. 

Oklahoma Primary Healthcare Improvement Cooperative

 

OPHIC is the implementation science arm of a statewide network to help improve healthcare delivery assisting primary care practices to adopt evidence-based best practices for the care of their patients.

OCTSI Clinical Research Unit

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The OCTSI CRU assists medical providers to identify and conduct clinical research opportunities in Oklahoma.

OSCTR Clinical Resources Space Availability

We would like all clinical investigators within our Oklahoma Shared Clinical and Translational Resources partner institutions to be aware that the OSCTR Clinical Research space in the Harold Hamm Diabetes Center is now open and available for your clinical research studies. We have a new clinical research coordinator, Janice Gales, who looks forward to aiding investigators with clinical research projects and regulatory assistance. Janice is a registered nurse who has been involved in clinical research on campus since 1995. 

Translating Practice into Research Program RFA

This year the OSCTR is starting a research training program.

Translating Practice into Research (TPIR), for healthcare professionals, clinical investigators, and basic scientists funded by the NIH Oklahoma Shared Clinical and Translational Resources grant. The goal of the TPIR trainee program is to produce a group of clinicians and scientists who have the ability to translate their clinical observations and ideas for improving practice into practical and feasible research projects. Attached is a detailed description. 

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Recent Publications

Associations between COVID-19 therapies and outcomes in rural and urban America: A multisite, temporal analysis from the Alpha to Omicron SARS-CoV-2 variants

J Rural Health. 2024 Jul 2. doi: 10.1111/jrh.12857. Online ahead of print.

ABSTRACT

PURPOSE: To investigate the enduring challenges in adverse COVID-19 events between urban and rural communities in the United States, focusing on the effects of SARS-CoV-2 vaccination and therapeutic advances on patient outcomes.

Neurovascular coupling, functional connectivity, and cerebrovascular endothelial extracellular vesicles as biomarkers of mild cognitive impairment

Alzheimers Dement. 2024 Jul 3. doi: 10.1002/alz.14072. Online ahead of print.

ABSTRACT

INTRODUCTION: Mild cognitive impairment (MCI) is a prodromal stage of dementia. Understanding the mechanistic changes from healthy aging to MCI is critical for comprehending disease progression and enabling preventative intervention.

Effect of prematurely elevated late follicular progesterone on pregnancy outcomes following ovarian stimulation-intrauterine insemination for unexplained infertility: secondary analysis of the AMIGOS trial

Hum Reprod. 2024 May 31:deae113. doi: 10.1093/humrep/deae113. Online ahead of print.

ABSTRACT

STUDY QUESTION: What is the relationship between late follicular phase progesterone levels and clinic pregnancy and live birth rates in couples with unexplained infertility undergoing ovarian stimulation with IUI (OS-IUI)?

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