The Oklahoma Shared Clinical and Translational Resources

The OSCTR is funded by the National Institutes of Health as part of its IDeA-CTR program. We have the mission to serve as a catalyst for clinical and translational research that improves health and healthcare for underserved and underrepresented populations, to provide training and infrastructure to help junior investigators to launch independent research careers, and to expand the opportunities of IDeA states and Oklahoma communities to participate in research that improves the health of our residents. 

Oklahoma Clinical and Translational Science Institute

 

OCTSI is the home of the OSCTR, as well as clinical research services and dissemination and implementation resources to help improve the delivery of healthcare. 

Oklahoma Primary Healthcare Improvement Cooperative

 

OPHIC is the implementation science arm of a statewide network to help improve healthcare delivery assisting primary care practices to adopt evidence-based best practices for the care of their patients.

OCTSI Clinical Research Unit

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The OCTSI CRU assists medical providers to identify and conduct clinical research opportunities in Oklahoma.

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OCTSI receives $15 million grant to improve heart health in Oklahoma

Submitted by Anonymous (not verified) on

OCTSI receives $15 million grant to improve heart health in Oklahoma

Researchers with the University of Oklahoma in Tulsa and Oklahoma City have received a $15 million grant to improve heart health in residents throughout the state.

OU is one of seven grantees in the nation for the award from the U.S. Department of Health and Human Services.

OSCTR Clinical Resources Space Availability

Submitted by Anonymous (not verified) on

We would like all clinical investigators within our Oklahoma Shared Clinical and Translational Resources partner institutions to be aware that the OSCTR Clinical Research space in the Harold Hamm Diabetes Center is now open and available for your clinical research studies. We have a new clinical research coordinator, Janice Gales, who looks forward to aiding investigators with clinical research projects and regulatory assistance. Janice is a registered nurse who has been involved in clinical research on campus since 1995. 

Translating Practice into Research Program RFA

Submitted by Anonymous (not verified) on

This year the OSCTR is starting a research training program.

Translating Practice into Research (TPIR), for healthcare professionals, clinical investigators, and basic scientists funded by the NIH Oklahoma Shared Clinical and Translational Resources grant. The goal of the TPIR trainee program is to produce a group of clinicians and scientists who have the ability to translate their clinical observations and ideas for improving practice into practical and feasible research projects. Attached is a detailed description. 

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Recent Publications

Avoidance of medical care among American Indians with a history of cancer during the coronavirus pandemic

Front Public Health. 2023 Nov 3;11:1265071. doi: 10.3389/fpubh.2023.1265071. eCollection 2023.

ABSTRACT

OBJECTIVES: Assess the percentage of cancer-related appointment delays, cancelations, and the unavailability of medications experienced by American Indian participants during the COVID-19 pandemic.

METHODS: This cross-sectional survey study was completed between October 2020 and July 2021 by 360 individuals with cancer who lived in California and Oklahoma. Binary and multivariate logistic regression analysis was completed in SAS 9.4.

Preexisting Autoimmunity Is Associated With Increased Severity of Coronavirus Disease 2019: A Retrospective Cohort Study Using Data From the National COVID Cohort Collaborative (N3C)

Clin Infect Dis. 2023 Sep 18;77(6):816-826. doi: 10.1093/cid/ciad294.

ABSTRACT

BACKGROUND: Identifying individuals with a higher risk of developing severe coronavirus disease 2019 (COVID-19) outcomes will inform targeted and more intensive clinical monitoring and management. To date, there is mixed evidence regarding the impact of preexisting autoimmune disease (AID) diagnosis and/or immunosuppressant (IS) exposure on developing severe COVID-19 outcomes.

Pharmacotherapy and pulmonary fibrosis risk after SARS-CoV-2 infection: a prospective nationwide cohort study in the United States

Lancet Reg Health Am. 2023 Aug 2;25:100566. doi: 10.1016/j.lana.2023.100566. eCollection 2023 Sep.

ABSTRACT

BACKGROUND: Pulmonary fibrosis is characterized by lung parenchymal destruction and can increase morbidity and mortality. Pulmonary fibrosis commonly occurs following hospitalization for SARS-CoV-2 infection. As there are medications that modify pulmonary fibrosis risk, we investigated whether distinct pharmacotherapies (amiodarone, cancer chemotherapy, corticosteroids, and rituximab) are associated with differences in post-COVID-19 pulmonary fibrosis incidence.

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