The Oklahoma Shared Clinical and Translational Resources

The OSCTR is funded by the National Institutes of Health as part of its IDeA-CTR program. We have the mission to serve as a catalyst for clinical and translational research that improves health and healthcare for Oklahomans, to provide training and infrastructure to help junior investigators to launch independent research careers, and to expand the opportunities of IDeA states and Oklahoma communities to participate in research that improves the health of our residents. 

Oklahoma Clinical and Translational Science Institute

 

OCTSI is the home of the OSCTR, as well as clinical research services and dissemination and implementation resources to help improve the delivery of healthcare. 

Oklahoma Primary Healthcare Improvement Cooperative

 

OPHIC is the implementation science arm of a statewide network to help improve healthcare delivery assisting primary care practices to adopt evidence-based best practices for the care of their patients.

OCTSI Clinical Research Unit

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The OCTSI CRU assists medical providers to identify and conduct clinical research opportunities in Oklahoma.

OCTSI on the Radio

OCAST Oklahoma Innovations will air this Saturday and Sunday on the stations below. It will be available on the OCAST website www.ok.gov/ocast/News_Media/Radio_Show , along with a transcript, on Monday. 

The week's program features OUHC research leaders discussing science and medicine in Oklahoma. Dr. Judith James, the Principal Investigator of the Oklahoma Shared Clinical and Translational Resources discusses the Oklahoma Clinical and Translational Science Institute and our projects. 

EvidenceNOW Grant Initiative Provides Support for Primary Care Practices in Oklahoma to Advance Cardiovascular Care

Heart disease remains the number one cause of death in the United States, claiming more lives than all cancers combined. Heart disease is also taking a toll on Oklahoma. But the evidence is clear—we can reduce the threat by applying the ABCS of cardiovascular disease prevention: Aspirin use by high-risk individuals, Blood pressure control, Cholesterol management, and Smoking cessation.

OCTSI receives $15 million grant to improve heart health in Oklahoma

OCTSI receives $15 million grant to improve heart health in Oklahoma

Researchers with the University of Oklahoma in Tulsa and Oklahoma City have received a $15 million grant to improve heart health in residents throughout the state.

OU is one of seven grantees in the nation for the award from the U.S. Department of Health and Human Services.

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Recent Publications

Neurovascular coupling, functional connectivity, and cerebrovascular endothelial extracellular vesicles as biomarkers of mild cognitive impairment

Alzheimers Dement. 2024 Jul 3. doi: 10.1002/alz.14072. Online ahead of print.

ABSTRACT

INTRODUCTION: Mild cognitive impairment (MCI) is a prodromal stage of dementia. Understanding the mechanistic changes from healthy aging to MCI is critical for comprehending disease progression and enabling preventative intervention.

Associations between COVID-19 therapies and outcomes in rural and urban America: A multisite, temporal analysis from the Alpha to Omicron SARS-CoV-2 variants

J Rural Health. 2024 Jul 2. doi: 10.1111/jrh.12857. Online ahead of print.

ABSTRACT

PURPOSE: To investigate the enduring challenges in adverse COVID-19 events between urban and rural communities in the United States, focusing on the effects of SARS-CoV-2 vaccination and therapeutic advances on patient outcomes.

Effect of prematurely elevated late follicular progesterone on pregnancy outcomes following ovarian stimulation-intrauterine insemination for unexplained infertility: secondary analysis of the AMIGOS trial

Hum Reprod. 2024 May 31:deae113. doi: 10.1093/humrep/deae113. Online ahead of print.

ABSTRACT

STUDY QUESTION: What is the relationship between late follicular phase progesterone levels and clinic pregnancy and live birth rates in couples with unexplained infertility undergoing ovarian stimulation with IUI (OS-IUI)?

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